Kylie Spelde, Janine Vaughan's sister, often speaks about the devastation her sister's disappearance has had on the family.

Ms Vaughan was last seen getting into a red car on Keppel Street in the early hours of December 7, 2001 after a night out with friends.

Ms Spelde said that moment changed her family's lives and she now can't imagine what a normal life would be.

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"If they do find her, what next?" she said.

"I've spent the last 19 years, all of my adult life, looking for Janine. I think about how I would go if they found her.

"What would my life be like if we didn't have to spend every day trying to find out the truth?

"My kids would have my full attention, my husband would have my full attention, but, at the moment, I really don't know what my life would be like."

Kiara White, the sister of missing Bathurst man Andrew Russell, told of a similar experience.

Mr Russell was last seen alive in June 2009 on his father's 40^th birthday. He had purchased a birthday card for his dad at a William Street newsagency but never got to give it to him.

Ms White said her family has no doubt there are people in Bathurst who know the truth and know where her brother's remains are buried.

"Some of these people have kids now. What they need to remember is Andrew was also someone's child," she said.

"What would they do if this happened to their child?

"I don't understand how they sleep at night having that weight on their shoulders ... Just come forward so we can put him to rest and have a place where we come and lay a flower.

"We will never give up hope and we will never give up believing that one day this nightmare will be finally over."

Ricki Small's daughter Jessica Small was just 15 when she was abducted from Hereford Street in 1997.

She described the last 23 years as a nightmare, saying that despite the passage of time she still lives with hope that one day she will find her daughter and be able to bring her home.

"I hope for the best, " she said.

"It's been a long time but some of these (cold) cases have been cracked.

"We all deserve answers. It's been a long time and it's been hard waiting, and I haven't seen too many people come forward with relevant information.

"But I will always hope and pray that Jessica will be found."

Ms Small said she was surprised that $1 million reward for information about Jessica's killer hadn't flushed out someone with information on the case.

"I thought that might have sparked something," she said, adding she pleaded to anyone with information to contact police.

Anyone with information on the disappearance of Jessica Small, Janine Vaughan or Andrew Russell is urged to contact Crime Stoppers on 1800 333 000.