Nathaniel Bower, 14, was last seen in the Kelso area about 1.45pm on Thursday.

Officers from Chifley Police District were notified a short time later and commenced inquiries into his whereabouts.

Police say Nathaniel has a medical condition for which he requires medication and concerns are held for his welfare due to his young age.

He is described as being of Caucasian appearance, about 145cm tall, of a thin build with light brown hair and brown eyes.

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Nathaniel was last seen wearing a black "puffa jacket, denim blue jeans, red t-shirt, black 'Nike' cap and black and white sneakers.

He resides in the Kelso area and is known to frequent Bathurst and Mount Druitt.

Anyone with information about Nathaniel's whereabouts is urged to contact Bathurst police on 6332 8699, Crime Stoppers on 1800 333 000 or https://nsw.crimestoppers.com.au. Information is treated in strict confidence.

The public is reminded not to report crime via NSW Police social media pages.

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