Western NSW Local Health District Chief Executive Officer Scott McLachlan, said on Wednesday the community still needed to be "extra cautious".

"This is a time for us to be aware, Covid could be creeping around Molong or our region.

"This is the time to be extra cautious."

The news came just minutes after the premier, Gladys Berejiklian announced as part of the State's fight against the Covid crisis in Sydney, 40,000 Pfizer doses will be allocated from NSW Health's rural and regional supply of COVID-19 vaccine to help Year 12 students in south west and western Sydney get back to school.

The Pfizer doses will be sourced from supplies across rural and regional NSW to ensure no one area is impacted.

Mr McLachlan said the redirection of vaccines would not leave regional communities vulnerable, saying GPs will continue to supply Pfizer vaccinations in regional NSW, and their supplies from the Federal Government are unaffected by this reallocation.

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He reassured the regional community vaccinations will still be available through the Local Health District, particularly AstraZeneca.

"We know there's a big volume of Pfizer and AstraZeneca available through GPs, Aboriginal Medical Services and respiratory clinics."

He encourage everyone to look at their eligibility for either dose on the vaccination eligibility checker.

He said they were taking stock of situation in Sydney.

"We know its getting to a really serious situation, and the intention is to try and get kids back to school, get work places resuming, and get life back to normal as soon as possible."

Mr McLachlan said he supports the move (to redirect regional vaccines) even if it does mean there is a need to constrain the supply of the vaccine in Western NSW to help out.

But he said they know is "there are a lot of vaccines still available particularly through GPs."

On Wednesday, NSW Health put out a statement assuring those in regional NSW who have had a first Pfizer dose they will receive their second dose.