They say items and substances seized will undergo forensic examination.

NSW Police says detectives from the Drug and Firearms Squad's Chemical Operations Team established Strike Force Vindin earlier this year to investigate a criminal syndicate involved in the supply of precursors and manufacture of prohibited drugs across NSW.

IN OTHER NEWS AROUND BATHURST:

Earlier this month, strike force detectives executed three search warrants at storage sheds at Prospect, in western Sydney, where they are alleged to have seized 150kg of methylamphetamine (ice) and 14kg of cocaine, with a combined estimated potential street value of $33 million.

Officers are also alleged to have seized $1.5 million cash, as well as large quantities of chemicals and solvents consistent with the manufacture of prohibited drugs.

As part of ongoing inquiries, NSW Police says strike force detectives executed a further six search warrants and two crime scene warrants at properties across Greater Sydney and Pyramul - about 70 kilometres north of Bathurst - from 6am on Thursday, August 12.

During the searches, officers say they seized more than $3.2 million cash, two rifles, luxury watches, electronic devices, documentation and several vehicles.

Detectives also say they located hundreds of litres of chemicals and approximately 400kg of liquid - believed to be unrefined cocaine - from a Pemulway residence.

At the remote rural property at Pyramul, police allege they uncovered a large, sophisticated clandestine laboratory.

During the initial deconstruction, officers say they located 15 kilograms of cocaine, as well as chemicals and thousands of litres of liquids.

They say further items, including cars, motorcycles and two air rifles, were also seized.

Police say two men - aged 33 and 54 - were arrested during a vehicle stop at Pyramul.

In a subsequent search of the Mitsubishi Triton, officers say they located several buckets containing 140kg of liquid - believed to be further unrefined cocaine.

The younger man was charged with five counts of supplying a prohibited drug (large commercial quantity), knowingly dealing with the proceeds of crime and participating in a criminal group that contributes to criminal activity. He was refused bail to appear at Lithgow Local Court on Friday, August 13.

The older man was issued a $1000 PIN for breaching the Public Health Order and released pending further inquiries.

Police say a further two men - aged 51 and 53 - were arrested at the Pyramul property and taken to Mudgee Police Station.

The younger man was charged with manufacturing a prohibited drug (large commercial quantity), supplying a prohibited drug (large commercial quantity), and participating in a criminal group that contributes to criminal activity.

The older man was charged with manufacturing a prohibited drug (large commercial quantity), supplying a prohibited drug (large commercial quantity), dealing with property proceeds of crime and participating in a criminal group that contributes to criminal activity.

Both men were refused bail to appear at Mudgee Local Court on Friday, August 13.

Officers say they are working with the Department of Home Affairs regarding the visa status of the older man.

Anyone with information that may assist Strike Force Vindin investigators is urged to contact Crime Stoppers: 1800 333 000 or https://nsw.crimestoppers.com.au. Information is treated in strict confidence. The public is reminded not to report information via NSW Police social media pages.

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